
This game is rated ESRB: Mature 17+ for Blood and Gore and Violence.
Released in 2008 for the Wii, The House of the Dead 2 & 3 Return is a compilation developed by H.I.C. that brings together two rail shooter entries from the series: The House of the Dead 2, originally released on Dreamcast, and The House of the Dead III, originally released on Xbox. Both titles were ported with support for the Wii Zapper peripheral. The collection adds new content to The House of the Dead III in the form of an unlockable Extreme mode, which raises the difficulty by increasing enemy attack speed and reducing the player's bullet blast radii to levels comparable to the handgun in the second game. This mode also introduces a faster shotgun reload and a new Guard Attack melee move that simultaneously deals damage and deflects incoming attacks, though it requires a cooldown period before it can be used again.

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HotD2: The game follows the fictional events of February 26, 2000, fourteen months after the 1998 Curien Mansion incident in The House of the Dead. AMS agent G has gone missing and his last known location is Venice, Italy. The city of Venice becomes chaotic when a strange zombie breakout takes place. American AMS agents James Taylor and Gary Stewart are dispatched, along with Amy Crystal and Harry Harris, to investigate and evacuate the populace. They suddenly encounter the impish Zeal, who had recently dealt with G. Upon finding G alive but wounded, James and Gary converse with him and G gives them a field journal showing the bosses and weak points. The pair are then met with a massive undead horde, similar to the kind from the Curien Mansion incident. They continue on, trying to save the town's civilians from the zombies. HotD3: The zombie infestation has spread all over the world, reducing the world into desolation with the civilization collapsing. In 2019 (16 years after the events of The House of the Dead 4), a paramilitary force led by retired AMS agent Thomas Rogan infiltrates the EFI Research Facility, a research center formerly owned by Dr. Roy Curien located in an unnamed place in Europe or North America, to investigate what led to the world's collapse. During the mission, his entire team is killed, until he and his second-in-command, Captain Dan Taylor are left. When they manage to find their answer in a giant laboratory, Death, a gigantic mutant who serves as the facility's security guard, kills Taylor and injures Rogan. While fighting to stay alive, Rogan is approached by an unidentified figure in a semi-corporate attire who offers help. Contact with him is lost. Two weeks later, on October 31, Rogan's daughter, Lisa, accompanied by his former partner, semi-retired agent "G", arrives at the facility to rescue him. While navigating through the facility, they fend off against hordes of undead creatures, before they encounter Death, whom they fight twice. Later, they fight a deformed sloth, The Fool, and a mutated tendrilous plant named The Sun. Along the way, Lisa muses to "G" how she has to live in the shadows of her well-known father and that she is often the subject of his comparison.
